NEUROLOGY

Neurology Expertise That Goes Beyond the Protocol

We Can Help with Your Neurology Clinical Trial

At Catawba Research, neurology is more than a therapeutic area—it is a core strength built through decades of scientific leadership, operational discipline, and successful execution of complex global studies. Our executive team, led by seasoned neuroscience experts including Dr. Andy Silverman, Dr. Jack McLane, and Julie Arnold, has collectively guided hundreds of CNS and neurology programs across Phase II and Phase III development.

From neurodegenerative disease to rare neurologic disorders and psychiatric-neurology overlap conditions, we understand the complexity of endpoint selection, patient identification, site performance, caregiver burden, and the operational realities that define success in these trials. Our teams know how to navigate difficult enrollment environments, demanding protocol requirements, and highly specialized site networks to deliver studies on time, on budget, and inspection-ready.

Simply put, we know how to execute neurology studies that demand both scientific rigor and practical delivery. That is why sponsors trust Catawba Research to help move important therapies forward with confidence.

A Roadmap to Neurology Study Success

• A highly experienced team of executive leadership, project managers, CRAs, medical monitors, data managers, biostatisticians, and medical writers with deep expertise in neurology and CNS development.
• Decades of sponsor-side and CRO leadership in designing, managing, and rescuing complex Phase II and III neurology trials.
• Strong expertise in endpoint strategy, rater training, centralized assessments, adjudication processes, and protocol optimization for challenging neurologic indications.
• Well-versed in managing global neurology studies requiring specialized investigators, difficult-to-recruit patient populations, and caregiver-dependent participation.

Proven Leadership in CNS Development

• Leadership experience spanning more than 100 full-service Phase II and III studies across global neuroscience development programs.
• Deep expertise built through leadership of one of the industry's largest CNS franchises, including operations across North America, Europe, and Asia Pacific.
• Strong relationships with high-performing neurology investigators, academic centers, and specialized site networks.
• Global delivery model supported by U.S.-based strategic oversight and cost-efficient operational execution through India for data management, biostatistics, medical writing, and clinical operations.

Experienced in Neurology Indications

• Alzheimer's Disease
• Parkinson's Disease
• Multiple Sclerosis
• Epilepsy
• Migraine
• Peripheral Neuropathy
• Neuropathic Pain
• Amyotrophic Lateral Sclerosis (ALS)
• Myasthenia Gravis
• Huntington's Disease
• Stroke Recovery
• Traumatic Brain Injury
• Sleep Disorders
• Depression with Neurologic Comorbidity
• Anxiety and CNS-Related Psychiatric Disorders
• Rare Neurologic Diseases
• Women's Health and Neuropsychiatric Disorders
• Cognitive Impairment Disorders

The Infrastructure & Knowledge To:

• Design a strategy that makes your neurology study operationally efficient and scientifically credible.
• Leverage long-standing relationships with leading neurology investigators, specialized site networks, and key opinion leaders.
• Guide sponsors toward the right countries, regions, and patient access strategies for complex enrollment needs.
• Support successful endpoint implementation through rater training, centralized assessments, and high-quality site execution.
• Help secure the right investigators and the right patients—ensuring your trial meets the strict demands of regulatory-ready neurology development.

We invite you to discuss your next neurology clinical trial with your Catawba Research team. We look forward to learning about your program and helping move your therapy from concept to market.